TY  - BOOK
AU  - Putterman, Chaim. Ed
AU  - Putterman,Chaim
AU  - Cowburn,David
AU  - Almo,Steven
TI  - Structural biology in immunology : structure/ function of novel molecules of immunologic importance 
SN  - 9780128033692
PY  - 2018///
CY  - London
PB  - Academic Press is an imprint of Elsevier
KW  - Immunology
KW  - Cancer
KW  - Immunoglobulin allotypes
KW  - Antigen-antibody reactions
KW  - Immune System Phenomena
KW  - Immune System Diseases
KW  - Neoplasms
KW  - Immunoglobulins
N1  - Includes bibliographical references and index; 1. Organization of Immunological Synapses and Kinapses -- 2. Principles of Protein Recognition by Small T-Cell Adhesion Proteins and Costimulatory Receptors -- 3. Synthetic Antibody Engineering: Concepts and Applications -- 4. Natural Killer Cell Receptor -- 5. Structure-Function in Antibodies to Double-Stranded DNA -- 6. The Role of the Constant Region in Antibody-Antigen Interactions: Redefining the Modular Model of Immunoglobulin Structure
N2  - Structural Biology in Immunology, Structure/Function of Novel Molecules of Immunologic Importance delivers important information on the structure and functional relationships in novel molecules of immunologic interest. Due to an increasingly sophisticated understanding of the immune system, the approach to the treatment of many immune-mediated diseases, including multiple sclerosis, systemic lupus erythematosus, rheumatoid arthritis, and inflammatory bowel disease has been dramatically altered. Furthermore, there is an increasing awareness of the critical role of the immune system in cancer biology. The improved central structure function relationships presented in this book will further enhance our ability to understand what defects in normal individuals can lead to disease
ER  -